Investigation of Electrochemical Properties of UA At Al2O3NP/CPE and Development of Voltammetric Method for its Determination in Serum

The electrochemical properties of uric acid (UA) were determined by cyclic voltammetry (CV) and square wave (SWV) at a carbon paste electrode modified with aluminum oxide nanoparticles (Al2O3NP/CPE) in 0.05 M pH 5.0 phosphate buffer. adsorption the molecule on Al2O3NP/CPE investigated number electrons transferred reaction was calculated. A new voltammetric method for determination UA human serum also proposed. linear operating range limit detection (LOD) found to be 0.1µM-230 µM 0.1µM, respectively. developed showed high reliability, reproducibility, accuracy precision.